Now available on the Optilite……….C-Reactive Protein (CRP). This assay is designed for the quantitative in vitro determination of CRP concentration in both serum and plasma (Table 1).
CRP is part of the pentraxins protein group. It can readily bind to damaged cell membranes and microbial polysaccharides, and is involved in the agglutination and precipitation of invasive bacteria. It can also activate complement, resulting in inflammation, opsonisation and phagocytosis of cell debris and bacteria.
This protein is synthesised in the liver and normal serum concentrations are typically around <10 mg/L. Increased concentrations occur rapidly following inflammation and raised serum levels may be detected within 6 hours. CRP is probably the most useful and reliable indicator of the acute phase response, being preferable to the erythrocyte sedimentation rate (ESR).

• Moderately elevated serum levels (10-40 mg/L) are associated with mild inflammation and viral infections.
• Higher concentrations (40 to 200 mg/L) occur with acute phase inflammation and bacterial infections.

Description	Product Code	Kit Size	Measuring Range	Sample Type
C-Reactive Protein	NK044.OPT	100 test	5-1425 mg/L	Serum, Urine

Table 1: New Optilite CRP assay technical details.

For more information or to order this assay please contact your local TBS office or distributor.

CRP is part of a comprehensive assay menu specifically designed for the Optilite which is our optimised protein system. The menu consists of our flagship Freelite®, Hevylite® and Subclasses as well as complement, renal function and specific proteins. Each assay has been specifically designed for use on Optilite to ensure optimal performance and confidence in results.